What are the requirements for a surrogate mother’s womb for IVF?

　　
　　Surrogate mother’s uterus is like the land, embryo is like the seed, the process of transfer is like the process of sowing, whether the seed will germinate and grow after planting depends on whether the soil is fertile, whether the sunshine and rainfall supply is sufficient.

　　At the time of transfer, the uterus should be of normal size and shape, the endometrium should be of moderate thickness, and there should be no uterine diseases. The presence of fibroids and adenomyosis usually affects the inability of the foetus to latch on and thus the success rate of the foetus. So, what are the requirements for a woman’s uterus to undergo IVF?
　　1. Endometrium
　　The endometrium is the mucous membrane that covers the uterine cavity and is one of the most differentiated tissues in the body, which changes with the ovarian cycle. If the endometrium is too thin, it will directly lead to the blastocyst not being able to successfully implant or not firmly implanted, and the blastocyst will be re-stripped due to insufficient nutritional supply, resulting in IVF failure.
　　In addition, endometritis, endometriosis, endometrial cancer and other causes are also the main reasons for female surrogate mothers to miscarry and IVF failure. If you want to increase the chance of IVF success, the endometrium of the surrogate mother should be healthy, and the thickness of the endometrium is more important, if the endometrium is within the normal range (8mm-12mm), so that the blastocyst transplantation can ensure that the blastocysts can be properly implanted and pregnancy.
　　2. Uterine fibroids
　　Uterine fibroids are the most common benign tumour in female reproductive organs and one of the most common tumours in human body. Uterine fibroids affect the success rate of IVF mainly related to the location, size and number of fibroids. If the fibroids are large in size, they will prevent the blastocyst from implanting, and even if the implantation is successful, when the foetus develops slowly, the foetus will be affected by the fibroids in the uterus, resulting in foetal malposition. When the foetus develops in the middle and late stages, the foetus will not be able to develop normally, which may cause premature birth and miscarriage.
　　3. Uterine malformation
　　Depending on the degree of uterine anomalies, the manifestations will be different. In the case of mild uterine malformation, there is no abnormality in menstruation, pregnancy and delivery, and it may remain undetected for a lifetime. However, in the case of severe uterine malformation, it may cause abnormal menstruation or infertility, and even if the embryo is successfully implanted through IVF, the uterus may not be able to change according to the foetus’s development because of the uterine malformation, which may cause miscarriage and preterm labour, and so on.
　　4. Insufficient corpus luteum
　　The corpus luteum of the ovary secretes luteinising hormone, which is a natural progesterone that has a significant morphological effect in the body on the endometrium that has been stimulated by oestrogen, and is necessary for the maintenance of pregnancy. Insufficient corpus luteum refers to the lack of formation of corpus luteum after ovulation of the ovary, so that progesterone secretion is insufficient, so that the endometrium fails to convert in time, and is not conducive to the implantation of the blastocysts, thus often leading to infertility or habitual miscarriage.
　　It is recommended that surrogate mothers, before undergoing IVF to help pregnancy, both husband and wife should first go to the hospital to do a detailed examination of physiological conditions, professional reproductive doctors will be based on the results of the examination as well as the patient’s specific situation to formulate a detailed IVF to help pregnancy programme, to maximize the pregnancy rate of IVF.